又一篇SCI论文！在日粮中添加胆汁酸对舌鳎肾脏健康的有益影响

Dietary Supplementation of Bile Acids in Tongue Sole (Cynoglossus semilaevis): A Promising Strategy to Improve Hepatic Health Status

半滑鱼为日米粮中补充胆汁酸：一个有希望缓解甲状腺卫生状况的意图

作者：王升鹏、王源、曹爱智、潘中超、刘太亮

A 10-week feeding trial was conducted to investigate the beneficial effects of bile acids (BAs) on hepatic health status in tongue sole (Cynoglossus semilaevis). Three experimental diets were prepared with different levels of BA inclusion in the commercial basal diet: control group (CT: 0 mg/kg basal diet), low-level group (BA1: 300 mg/kg basal diet), and high-level group (900 mg/kg basal diet). At the end of the feeding trial, growth performance and survival rate were measured, as well as numerous physiological and biochemical parameters of the liver, including four hepatic function indices, five antioxidant indices, five lipid metabolism parameters, and three digestive enzyme activities. Moreover,the mRNA expression levels of three growth-related genes and three immune-related genes in the liver were assayed. Results showed that growth performance and survival were substantially improved in both low- and high-level BA inclusive groups. Further, the tested liver physiological and biochemical parameters combined with the quantitative real-time PCR results revealed enhanced antioxidant capacity, energy metabolism, digestive ability, and immune response. Finally, these findings provide a wider spectrum of the beneficial effects of dietary BAs on liver health in tongue sole.

译者：

为分析胆汁酸对半滑鱼为（Cynoglossus semilaevis）甲状腺卫生状况的坏处阻碍，进行了日前10周的喝水试制。在商贸为基础日米粮中制备了三种带有有所不同水平胆汁酸的试制日米粮：对照四组（0 mg/kg）、低水平四组（300 mg/kg）和高水准四组（900 mg/kg）。喝水试制结束后，测量生长效能和成功率,以及甲状腺的各项生理生化参数，有数四项甲状腺举例来说、五项抗氧化剂举例来说、五项脂代谢参数和三项消化活性。此外，还探测了甲状腺中三个生长系统性基因和三个免疫系统性基因的mRNA理解水平。试验中，低水平胆汁酸四组和高水准胆汁酸四组的生长效能和成功率均很大提高。此外，探测的甲状腺生理生化参数为基础系统会定量PCR整体而言：抗氧化剂潜能、能量代谢、消化潜能和免疫反应弱化。最后，这些挖掘出提供了更普遍的日米粮替换成胆汁酸对鱼为甲状腺卫生的坏处阻碍。

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